祛淤消斑胶囊对动脉粥样斑块组织学构成的临床研究

Clinical Research on Histological Structure of "Quyu Xiaoban Capsule" on Arterial Atheromatous Plaque

观察 58例动脉粥样硬化患者 ,根据其斑块不同病变类型分为脂质型斑块、纤维脂质型斑块、钙化型斑块、溃疡型斑块四组 ,均给予祛淤消斑胶囊治疗 8个月 ,观察其对不同类型斑块组织学构成的影响。结果除溃疡型外 ,各型斑块的组织学构成在用药前后均有不同程度的变化 ,其变化最大的为脂质型斑块 (P <0 0 5) ,纤维型斑块次之 ,钙化型斑块变化率最小 ,提示祛淤消斑胶囊能在一定程度上改变斑块的组织学构成 ,增大斑块的密度 ,起到稳定斑块的作用 ,从而减少急性心脑血管疾病的发生率。

The plaque in 58 cases were categorized into lipid,fibrous,calcified and ulcerative plaque,and treated with 'Quyu Xiaoban Capsule'for 8 months.Meanwhile,the plaque was histologically observed.After treatment,the histological tissues of the plaque improved,with varying degrees,the lipid plaque first ( P <0 05),fibrous plaque second and calcified plaque third.It is revealed that the Capsule can change histological structure,increase the plaque density and stabilize the plaque,as a result,to reduce the occurrence of the acute cardio-cerebrovascular accidents.