牛膝多糖对小儿反复呼吸道感染的影响

Influence of Achyranphes Bidentata Polysaccharides on Infantile Recurrent Respiratory Infection

为观察牛膝多糖对小儿反复呼吸道感染的影响 ,将 40例患儿随机分成治疗组 30例和对照组 10例 ,治疗组口服牛膝多糖合剂 ,对照组腋下注射TF ,均以 12周为一疗程 ,作治疗前后 3个月中复感次数、胃纳、多汗情况及血清Ig、外周NK细胞活性比较 ,并在治疗组中取 10例年龄较大者 ,观察其治疗前后性激素水平的变化。结果 :治疗组临床有效率为 83 3% ,胃纳、多汗情况有一定改善 ;对照组临床有效率为30 .0 % ,胃纳、多汗情况无明显变化。治疗组血清Ig治疗后有明显提高 (P <0 0 1) ,NK细胞活性也有提高 ,性激素水平无明显变化 ;对照组治疗前后均无显著变化。提示牛膝多糖是防治小儿复感的有效制剂。

To observe the curative effects of achyranphes bidentata polysaccharides (ABP) in treating recurrent respiratory infection in children and its influence on immunostimulation and gender hormone,30 cases were treated with ABP for 3 months.Each time respiratory infection was recorded,serum IgG,IgA,IgM,FSH,LH,PRL,E 2,T and active NK cells were detected.Results showed that the short-term effects amounted to 83 3%;serum immunoglobulin and active NK cells were elevated,gender hormone were undifferentiated.