相转移催化合成对硝基苯乙醚的研究

A STUDY ON SYNTHESIS OF P-NITROPHENETOL BY PHASE TRANSFER CATALYSIS

对相转移催化合成对硝基苯乙醚工艺进行了研究 ,通过对催化剂的选择、反应条件的优化及母液与催化剂的套用试验 ,讨论了影响产物质量和收率的有关因素 ,确定出相转移催化合成对硝基苯乙醚的最优的工艺条件。用本工艺生产的对硝基苯乙醚质量分数达 99.5 %以上 ,凝固点≥ 5 7.0℃ ,收率达到 95 %以上。该工艺与传统的合成方法相比具有反应条件温和、反应周期短、又可省去乙醇回收。

This paper studies the synthesis process of p nitrophenetol by phase transfer catalyist.The Effect factors on the quality and the yield of the product are discussed by a series of experiment which include selecting of the catalyst and optimizing of reaction and recycling of liquid and catalyst.The best technological conditions are determined. The content of the p nitrophenetol is over 99.5%.The mp of the product is over 57?℃ and the yield reaches to 95%.This process has the adventage of gentle reaction and short period and avoiding reuse of ethylalcohol and higher yield and less pollution.