胸膜恶性间皮瘤临床病理分析

Clinical pathological analysis about pleural malignant mesothelioma

目的 对胸膜恶性间皮瘤进行临床病理分析，提高诊断及治疗水平，减少误诊率。方法 收集１９７５～１９９９年诊治病例，复习Ｘ光、Ｂ超及细胞病理资料。结果 ８０％病人临床上有胸痛且进行性加重，并有胸腔积液。Ｘ光有局限性胸膜增厚，胸水显示出现恶性瘤细胞，病理切片有双向分化特点。结论 对中年人胸部剧烈疼痛伴有胸腔积液时，应首先考虑本瘤，该瘤的确诊应依赖临床、影像学及细胞病理学。

Objective Make clinical pathlogical analysis to pleural malignant mesothelioma, and enhance the diagnostic and therapeutic level, and reduce the mistake diagnosis rate. Methods Collect the cases diag- nosed and treated from 1975?999, review X-ray. B-type ultrasound and cellular pathologic data. Results above 80% patients have pectoralgia and demonstrate progressive aggravating, and have pleural hydrops. The character of X-ray shows that located pleural incrassation, and find malignant tumor cells in thorax water, and have the character of double differentiation in pathologic section. Conclusion If middle aged pa- tients have the sympton of drastical pain in chest and company with thorax hydrops, we should considerate this disease first, and the diagnosis of this kind of tumor should depend on clinic, image and cellular pa- thology.