42例青年人胃癌临床分析

Clinical analysis of youth gastric cancer:a report of 42 cases

目的总结青年人胃癌的临床病理特点以指导治疗。方法回顾性分析１９８５年 １月～１９９５年５月收治的４２例≤３５岁的青年人胃癌。结果 ①手术切除率为９０．５％，其中根治性切除率占７１．４％；②青年人胃癌以女性多见，男女之比为１：１．３；③临床表现缺乏特征性，误诊率高达４２．８％；④组织学分化差，分期偏晚，以ＢｏｒｒｍａｎｎⅢ型，Ⅳ型居多；⑤预后差，五年生存率仅为２１．４％；⑥根治性切除组与姑息性切除组及单纯探查组１、３、５年生存率差异具有显著性意义（Ｐ＜０．０５）；Ⅰ＋Ⅱ期与Ⅲ＋Ⅳ期３、５年生存率差异亦具有显著性意义（Ｐ＜０．０５）。结论欲改善青年人胃癌的预后，早期诊断、减少误诊及早提高根治性切除率是关键。

：Objective By mains of analysing the clinical and patholigic characteristics of youth gastric cancer,to investigate the surgical treatment.Methods 42 cases of youth gastric cancer treated in our hospital in 1985-1995 were analyzed retrospectively.Results Resection rate is 90.5% and the radical resection rate is 71.4%. The rate of male vs female is 1：1.3. Clinical manisfestions is not specific, Which induced misdiagnosis rate is as high as 42.8%.The poor histologic defferentiation and BorrnannⅢ,Ⅳtype are prevalent.The prognosis is poor and the overall 5-year survival rate is 21.4%.The 1、3、5-year survival rate between radical resection group and palliative resection or laparotomy group is different (P<0.05).ConclusionEarly dignosing and raising radical resection rate lead to improving prognosis and decreasing the misdiagnose rate of youth gastric cancer.