补肾化毒法治疗SLE的理论机制探讨

Mechanism of Method of Tonifying Kidney and Removing Toxins in Treating SLE

用补肾化毒中药“狼疮静颗粒”治疗活动性SLE取得较好疗效 ,动物实验明确了该药对狼疮动物模型的部分免疫机理。本文着重探讨了补肾化毒法治疗SLE的理论机制。通过 1 96 7例SLE临床证型分析 ,探讨了SLE病变机理 ;通过理论分析 ,认为本病肾虚为本 ,毒瘀为标 ;基于病机 ,方附法出 ;最后指出补肾化毒法不是活动性SLE唯一治法 ,临症应重视辨证。

Satisfactory result has been obtained in the treatment of SLE with 'Langchuangjing Granule' for tonifying the kidney and removing toxins. Animal experiments have proved part of the immune mechanism of this medicine on animal models. This paper deals mainly with the mechanism of the method of tonifying the kidney and removing toxins in the treatment of SLE based on analysis of 1 967 SLE cases. The authors believe that the basic cause of the disease is kidney deficiency and the manifestation is the toxin and stasis. The authors also present methods and prescriptions for the disease and point out that the method under discussion is not the only method for the disease and that attention should be paid to syndrome differentiation in treating the disease.