辨证贴药对过敏性哮喘患者IL-5及ECP的影响

Effect of Acupoint Application Based on Syndrome Differentiation on Contents of IL-5 and ECP in the Patient of Allergic Asthma

目的 :探讨穴位敷贴的治哮机制。方法 :将 2 0 9例哮喘患者随机分为 2组 ,其中辨证贴药组12 5例 ,脱敏组 84例 ,分别观察两组治疗前后白介素 5 (IL 5 )及嗜酸性阳离子蛋白 (ECP)水平。 结果 :穴位敷贴后患者的IL 5及ECP含量明显降低 ,与治疗前比较差异具有显著性意义 (P <0 0 1;P<0 0 5 ) ,且辨证贴药组对IL 5的影响程度明显大于对照组 ,组间比较差异有显著意义 (P <0 0 5 )。结论

Purpose To probe into the mechanism of acupoint application treating asthma Methods Two hundred and nine cases of asthma were randomly divided into syndrome?differentiation acupoint application group(125 cases) and desensitization group(84 cases), and interleukin?5(IL?5) and eosinophilic cation protein(ECP) levels were observed before and after treatment respectively Results The IL?5 and ECP levels after acupoint application decreased significantly as compared with that before treatment( P <0 01, P <0 05), and the syndrome?differentiation acupoint application group had a larger effect on IL?5 content as compared with the control group( P <0 05) Conclusion Mechanism of acupoint application treating asthma is carried out possibly through a series of cytokines and toxic proteins