外科手术患者丙型肝炎病毒感染调查

Study on Hepatitis C Virus Infection of Patients Treated by Surgery

目的 调查外科患者HCV感染情况。方法 采用酶联免疫吸附的方法和逆转录 -聚合酶链反应 (PT -PCR)方法进行HCV测定。结果 2 5 5 0 0例外科患者中HCV感染率为 3 15 %,其中泌尿外科组HCV感染率最高(13 11%) ,显著高于其它科 (P <0 0 1) ;其余外科组与正常组相比较差异不显著 (P >0 0 1)。抽取 5 0 0例HCV感染的病例 ,应用PT -PCR检测HCVRNA ,阳性率为 77 2 %。结论 透析患者是HCV感染的高危人群 ,加强HCV早期感染的检测十分重要。

Objective To investigate the hepatitis C virus infection of patients treated by surgery.Methods Anti-HCV was detected with methods of ELISA and PT-PCR.Results The positive rate of anti-HCV was 3.15% in 25 500 cases treated by surgery.The infection rate of patients treated by hemostasis(13.11%) was significantly higher than those from other departments(P<0.01).There was not significant differnece between the other patients and the health controls(P>0.05).However the positive rate of HCV RNA was 77.2% in 500 cases of HCV.Conclusion The patients with hemostasis were at high risk of HCV infection,it was very important to detect potential infection.