摘要
观察咪唑安定对神经外科术后躁动病人的镇静作用。发现给予咪唑安定负荷剂量静注后 ,躁动病人 93 %的时间镇静效果满意 ,平均剂量 0 .0 86mg/kg,达到Ramsay 3级镇静水平。持续静脉输注咪唑安定 [药量平均 0 .0 8mg/ (kg·h) ],停药后苏醒时间短 ,长时间应用未见蓄积作用 ,镇静程度易控制 ,不良反应少。
The purpose of this research is to study the sedative action of midazolam in the treatment of neurosurgically post operative restlessness. Patients were intravenously given midazolam loading dosage (average 0.086 mg/kg), and during 93% of the whole period patients could reach level 3 of Ramsay sedative condition. The intravenous maintaining midazolam dosage was about 0.08 mg/(kg·h), patients could awake quickly after the drug withdraws and there was no evidence of accumulation after long term midazolam usage. The use of midazolam in neurosurgical post operative restlessness is associated with easily controled sedative level, less side effect and specific antagonist.
出处
《首都医科大学学报》
CAS
2001年第4期357-358,共2页
Journal of Capital Medical University
关键词
躁动
镇静
咪唑安定
神经外科
手术后
post operative restlessness
intravenous sedation
midazolam
