5Lenschow D J,Walunas T L,Bluestone J A,et al.CD28/B7 system of T cell costimulation[J].Annual Review of Immunology,1996,14:233-258.
6Polito L,Bortolotti M,Farini V,et al.Saporin induces multiple death pathways in lymaphoma cells with different intensity and timing as compared to ricin[J].The Internaional Journal of Biochemistry & Cell Biology,2009,41(5):1055-1061.
7Tazzari P L,Polito L,Bolognesi A,et al.Immunotoxins containing recombinant anti-CTLA-4 single-chain fragment of variable antibodies and saporin:in vitro results and in vivo effects in an acute rejection model[J].J Immunol,2001,167(8):4222-4229.
8Zeng L,Wan L,Chen L,et al.Selective depletion of activated T cells by recombinant immunotoxin containing anti-CTLA-4 single-chain fragment of variable antibody and N-terminal fragment of perforin[J].Transplant Proc,2006,38(7):2151-2153.
10Orbach A,Rachmilewitz J,Parnas M,et al.CTLA-4-Fasl induces early apoptosis of activated T cells by interfering with anti-apoptotic signals[J].J Immunol,2007,179(11):7287-7294.
