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神经干细胞研究新进展及临床应用展望 被引量：3

Progress in neural stem cells research and prospects of its clinical application
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摘要 The discovery of neural stem cells and deep researches on them are bringing us new hopes for treating nervous system diseases. This review focuses on the discovering processes of neural stem cells, the basic characteristics, the trans differentiation, and the advances in research methods. Also the application and potential values of neural stem cells in clinical therapy are detailed. The discovery of neural stem cells and deep researches on them are bringing us new hopes for treating nervous system diseases. This review focuses on the discovering processes of neural stem cells, the basic characteristics, the trans differentiation, and the advances in research methods. Also the application and potential values of neural stem cells in clinical therapy are detailed.
作者 汪璇 张浣清 朱艳霓 沈丽 李凌松
机构地区 北京大学干细胞研究中心
出处 《北京大学学报（医学版）》 CAS CSCD 北大核心 2001年第6期571-575,共5页 Journal of Peking University:Health Sciences
关键词 神经再生 神经系统疾病 神经干细胞 Stem cell Nerve regeneration Nervous system diseases/ther
分类号 Q21 [生物学—细胞生物学] R741 [医药卫生—神经病学与精神病学]
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参考文献4

  • 1Sanchez Ramos J，Exp Neurol，2000年，164卷，247页
  • 2Uchida N，Proc Natl Acad Sci USA，2000年，97卷，14720页
  • 3Ling Z D，Exp Neurol，1998年，149卷，411页
  • 4Svendsen C N，Exp Neurol，1997年，148卷，135页

同被引文献29

  • 1[1]Woodbury D, Schwarz EJ, Prockop DJ, et al. Adult rat and bone marrow stromal cells differentiate into neurons [J]. J Neurosci Res, 2000; 61(4): 364-370.
  • 2[2]Erices A, Conget P, Minguell JJ. Mesenchymal progenitor cells in human umbilical cord blood [J]. Br J Haematol,2000; 109(1): 235-242.
  • 3[3]Hou L, Cao H, Wang D, et al. Induction of umbilical cord blood mesenchymal stem cells into neuron-like cells in vitro [J]. Int J Hematol, 2003; 78(3): 256-261.
  • 4[4]Bicknese AR, Goodwin HS, Quinn CO, et al. Human umbilical cord blood cells can be induced to express markers for neurons and glia [J]. Cell Trasplant, 2002; 11(3): 261-264.
  • 5[5]Sanchez-Ramos JR, Song S, Kamath SG, et al. Expression of neural markers in human umbilical cord blood [J]. Exp Neuroi, 2001; 171(1): 109-115.
  • 6[6]Buzanska L, Machaj EK, Zablocka B, et al. Human cord blood-derived cells attain neuronal and glial features in vitro [J]. J Cell Sci, 2002; 115(10): 2131-2138.
  • 7[8]Ha Y, Lee JE, Kim KN, et al. Intermediate filament nestin expressions in human cord blood monocytes (HCMNCs) [J].Acta Neurochir (Wien), 2003; 145(6): 483-487.
  • 8[10]Li Y, Chopp M, Chen J, et al. Intrastriatal transplantation of bone marrow nonhematopoietic cells improves functional recovery after stroke in adult mice [J]. J Cereb Blood Flow Metab, 2000; 20(9): 1311-1319.
  • 9[11]Lu D, Sanberg PR, Mahmood A, et al. Intravenous administration of human umbilical cord blood reduce neurological deficit in the rat after traumatic brain injury [J]. Cell Transplant, 2002; 11(3): 275-281.
  • 10[12]Chen J, Sanberg PR, Li Y, et al. Intravenous administration of human umbilical cord blood reduces behavioral deficits after stroke in rats [J]. Stroke, 2001; 32(11): 2682-2688.

引证文献3

二级引证文献9

北京大学学报（医学版）
2001年 第6期

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