摘要
报道用高效液相色谱法(HPLC)对上海信谊制药厂生产的治疗心血管疾病的盐酸地尔硫(DTZ)片剂与日本产的DTZ片剂作了正常人口服后的生物利用度对照比较,结果表明:两种片剂的生物利用度相同(国产片为进口片的98.2％)。
This report was a comparison of the bioavailability in normal humen to takethe tablets of the cardiovascular drug--Diltiazem (DTZ) of Shanghai Xin-yiPharmaceutical Factory and Japan using high performance liquid chromatogra-phy (HPLC). The results were shown that both of the preparations almost similar on acsorption, metabolism and excretion.
出处
《上海医科大学学报》
CSCD
1991年第2期129-132,共4页
Journal of Fudan University(Medical Science)
关键词
盐酸地尔硫zuo
高效液相色谱
ciltiazem
high performance liquid chromatography
nomal human
bioavailability
