摘要
作者于1983～1988年收治胆管扩张症81例。66例检测血、尿淀粉酶,14例有高淀粉酶血症(>300Somoygi 单位).和高淀粉酶尿症(>500Somoygi 单位)并伴有类似急性胰腺炎的临床症状。然而,手术均未发现急性或慢性胰腺炎改变。提示胰液中的淀粉酶通过共同通道从胰管返流进入胆总管,损伤胆管壁,引起水肿和梗阻,并且在胆管内压增加时通过毛细胆管进入血液而导致高胰淀粉酶血症。
From 1983 to 1988,81 cases of congenital choledochal dilatation were admitted andblood and urine amylase were determined in 66 of them.Fourteen were found having hyperamylasemia(over 300 Somoygi units)and hyperamylasuria(over 500 Somoygi units)with clinical manifestations suggestive of acute pancreatitis.However,during operation not a single case showed evidence of acute or chronic pancreatitis.It is postulated that the hyperamylasemia was caused by flow of pancreatic juice from the pancreatic duct into thebiliary tree through the common channel.The amylase injured the epithelial lining of thebiliary tree,causing edema and obstruction,resulting in incresased pressure in the biliarytree and diffusion of amylase through the wall of the biliary capillary into blood stream.
出处
《上海医学》
CAS
CSCD
北大核心
1991年第3期125-127,共3页
Shanghai Medical Journal
