改良Webster症状评分量表在帕金森病手术疗效评估中的意义

THE SIGNIFICANCE OF USING MODIFIED WEBSTER SCALE IN EVALUATING THE EFFECT OF SURGICAL TREATMENT ON PARKINSON DISEASE

应用改良Webster症状评分表 ,对 42例帕金森病人分别在手术前后进行 10组症状记分。结果显示 ,术前评分为 (19 90± 5 2 7)分 ,术后为 (10 5 7± 6 10 )分 ,平均改善 (8 95± 3 37)分。其中特别显效 4例 (9 5 % ) ,显效 17例 (4 0 5 % ) ,有效 16例 (38 1% ) ,总有效率为 88 1%。单靶点毁损 34例 ,改善 (8 5 9± 3 5 3)分 ;双靶点 8例 ,改善 (10 0 0± 4 14)分 ,两组差别无统计学意义。提示对于药物疗效降低以及出现毒副反应的帕金森病患者 ,采用改良Webster症状评分量表有利于判定手术疗效 ,便于随访观察。该量表操作简便 ,尤其适用于神经外科医生应用 。

With Modified Webster Scale, 42 patients suffered from Parkinson disease were examined before and after operation. The symptoms were divided into 10 groups. 1～10 points was taken as slight disability, 11～20 as medium, and 21～30 as severe. Improvement less than 25% was taken as no effect, 26%～50% as effective, 51%～75% as significantly effective, and over 75% as very significantly effective. The score was (19 90±5 27) preoperatively and (10 57±6 10) postoperatively. The mean improvement was (8 95±3 37). Very significantly effective result was obtained in 4 cases (9 5%), significantly effective sesult was obtained in 17 cases (40 5%), and effective result was obtained in 16 cases (38 1%). The total effective rate was 88 1%. One target coagulation was performed in 34 cases, the mean improvement was in (8 59±3 53). Two target coagulation on one side was performed in 8 patients, the mean improvement was in (10 00±4 14). No significant difference was found between these two groups statistically. It is suggested, for patients with Parkinson disease in whom drug treatment is not efficacious or because of increased side effect, Modified Webster Scale is useful to evaluate the effect of surgical treatment. This scale is very easy to use especially for neurosurgeons.