儿童急性白血病血清铁蛋白和白细胞内铁蛋白含量的临床意义

CLINICAL SIGNIFICANCE OF SERUM AND LEUKOCYTE FERRITIN IN CHILDREN WITH ACUTE LEUKEMIA

本文观察了110例儿童急性白血病患者血清铁蛋白(SF)和白细胞内铁蛋白(WBC·F)与病情的关系.发现治疗前患者 SF 和 WBC·F 明显升高,二者均随着缓解期的延长而逐渐下降,可作为病情监测的指标。WBC·F 较 SF 能更为敏感可靠地反映白血病的病情变化,动态观察缓解期患者的 WBC·F 可能有助于预报复发。

The serum ferritin(SF)and leukocyte ferritin(WBCF)of 110 children in differentperiods of acute leukemia were determined.It showed that the concentrations of SF andWBCF increased markedly in untreated cases and decreased gradually with the durationof complete remission.SF and WBC F were closely related with the progress of thedisease.They may serve as indices to evaluate the effect of treatment and to estimate theprognosis,however WBC F is more informative than SF in estimating the progress.Thestudy also suggests that WBC F may be helpful in predicting relapse.