摘要
目的 为探讨尿液α1 微球蛋白在儿童某些疾病中的变化及其在肾脏疾病的诊断意义。方法 采用放免法 ,测定了 32例正常儿童的尿液α1 微球蛋白作为对照 ;检测患儿 12 2例 ,含肾疾患 2 1例 ,肺炎 31例 ,其它非肾脏损害病儿 2 7例 ,糖尿病 43例 ,同时检测了尿 β2 微球蛋白、α1 微球蛋白和微白蛋白 ,分别与正常对照组进行t检验分析。结果 肾疾患和肺炎组的尿α1 微球蛋白明显增高 ,差异有显著性。结论 尿α1 微球蛋白测定 ,可作为一种判定肾脏早期损伤的敏感指标。
Objective To investigate the change of the level of alpha 1 microglobulin in urine of children suffered from some diseases and the significance of diagnosing kidney disease.Methods Concentrations of alpha 1 microglobulin,beta 2 microglobulin and albumin in urine samples of 122 cases(21 case of kidney disease,31 pneumonia,43 diabetes and 27 other disease) and 32 normal children were determined by radioimmunoassay and the data from the determinations were analysed with t test. Results There was a statistically significant increase of alpha 1 microglobulin concentration in urine in kidney disease and pneumonia groups.Conclusion Urine alpha 1 microglobulin is a sensitive indicator for the determination early damage of kidney tubular.
出处
《河北医药》
CAS
2001年第2期102-103,共2页
Hebei Medical Journal
