克林霉素磷酸酯阴道片对阴道刺激反应的实验研究

Vaginal irritation following intravaginal administration of clindamycin phosphate vaginal tablet

目的 研究克林霉素磷酸酯阴道片对阴道的刺激反应。方法 阴道片直接给药法。结果 克林霉素磷酸酯阴道多次给予家兔阴道后 ,家兔全身状况良好 ,阴道口未见红肿及异常分泌物流出 ,肉眼及镜下观察取出的阴道组织 ,均未见异常。

AIM To study the vaginal irritation following intravaginal application of clindamycin phosphate vaginal table. METHOD Intravaginal administration of clindamycin phosphate vaginal tablet. RESULTS After intravaginal administration of clindamycin phosphate vaginal tablet, The rabbits general condition was good; The vulvovaginal was not red, swollen and did not have abnormal excretion. The vaginal tissue examined was normal by observation of naked eye and microscope. CONCLUSION Clindamycin phosphate vaginal tablet had not vaginal irritation following intravaginal administration.