2Reed J A, Loganzo F, Shea C R, et al. loss of expression of the p16/cyclin-dependent kinase inhibitor 2 tumor suppressor gene in melanocytic lesions correlated with invasive stage of tumor progression[J].Cancer Res, 1995, 55(13): 2713.
3Zhang Y,Xiong Y. Mutations in human ARF exon 2 disrupt its nucleolar localization and impair its ability to block nuclear export of MDM2 and p53[J]. Mol Cell, 1999,3(5):579-591.
4Ohta M, Nagai H, Shimizl M, et al. Rarity of somatic and germline mutations of the cyclin-dependent kinase 4 inhibitor gene, CDK4I, in melanoma[J].Cancer Res, 1994,54 (20):5269-5272.
5Travis J. Closing in on melanoma susceptibility gene(s)[J]. Science, 1992,258(5085): 1080- 1081.
6Diaz M O, Rubin C M, Harden A, et al. Deletions of interferon genes in acute lymphoblastic leukemia[J].N Engl J Med, 1990,322(2):77-79.
7James C D, He J, Collins V P, et al. Localization of chromosome 9P homozygous in glioma cell Lines with markers constituting a continuous linkage group[J]. Cancer Res, 1993, 53(16) :3674-3675.
8Cheng J, Jhanwar S C, Lu Y, et al. Homozygous deletions within 9P21 P22 indentify a small critical region fo chromosomalloss in human malignant mesotheliomas[J].Cancer Res, 1993, 53(20):4761-4763.
9Serrano M, Hannon G J, Beach D. A new regulatory motif in cell-cycle control causing specific inhibition of Cyclin D1/CDK4[J].Nature, 1993, 366(6456):704-707.
10Kamb A, Gruis N, Weaner-Feldhaus J, et al. A cell cycle regulator potentially involved in genesis of many tumor types[J].Science, 1994, 264(5157):436-440.
