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美洲商陆抗病毒蛋白研究进展 被引量：12

Prospect of study on pokeweed antiviral proteins
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摘要 美洲商陆抗病毒蛋白(pokeweedantiviralproteins,PAP)是一类具多种生物功能和活性的蛋白,本文在阐述了该类蛋白的生化等特性的同时,综述了该类蛋白在抗植物病毒、抗动物病毒以及用作免疫毒素等方面的研究进展。 Pokeweedantiviralproteins(PAPs)abstractedfromPhytolaccaamericanaisa groupof proteinshavingmany kindsof biologicalfunctionsandbiologicalactivities.The paperreviewspartialcharacteristicsof PAPsandpractical applicationinantivirusandpreparationof immunotoxinscontainingPAPs.
作者 付鸣佳 吴祖建 林奇英 谢联辉
机构地区 福建农林大学植物病毒研究所
出处 《生物技术通讯》 CAS 2002年第1期66-71,共6页 Letters in Biotechnology
基金 福建省科技厅重点项目(99-Z-193)资助
关键词 美洲商陆 抗病毒蛋白 核糖体失活蛋白 抗病毒作用 免疫毒素 研究进展 pokeweedantiviralproteins ribosome-inactivatingproteins antivirus immunotoxins
分类号 R284.1 [医药卫生—中药学] Q946.1 [生物学—植物学]
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  • 1Irvin JD. Purification and partial characterization of the antiviral protein from Phytolacca americana which inhibits eukaryotic protein synthesis[J]. Arch Biochem Biophys, 1975, 169:522
  • 2Irvin JD, Kelly T, Robertus JD. Purification and properties of a second antiviral protein from Phytolacca Americana which inactivates eukayotic ribosomes[J]. Arch Biochem Biophys, 1980, 200:418
  • 3Barbieri L, Aron GM, lrvin JD, et al. Purification and partial characterization of another form of the antiviral protein from the seeds of Phytolacca american a L. (pokeweed)[J]. Biochem J, 1982. 203(1): 55
  • 4Bolognesis A, Barbieri L, Abbondanza A, et al. Purification and properties of new ribosome inactivating proteins with RNA N-glycosidase activity[J]. Biochem Biophs Acta, 1990, 1087:293
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  • 8Poyet JL, Radom J, Hoeveler A. Isolation and characterization of a cDNA clone encoding the pokeweed antiviral protein II from Phytolacca amaericana and its expression in E. coli[J]. FEBS Left, 1994, 347(2-3):268
  • 9Houston LL, Ramkrishnan S, Hermodson MA. Seasonal variation in different forms of pokeweed antiviral protein, a potent inactivator of ribosomes[J]. J Biol Chem, 1983, 256:9601
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生物技术通讯
2002年 第1期

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