期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

分子生物学技术在动物营养学中的应用与发展前景 被引量：6

Application and prospects in anlmal nutrition of molecular biotechnology
下载PDF
导出
摘要 分子生物学理论与技术的发展和应用已渗透到生命科学的各各领域,动物营养学的发展需要在分子水平上分析及解释营养素对动物机体的生理、病理变化调控,如生长发育、新陈代谢、遗传变异、免疫与疾病等。本文综述了分子生物学在动物营养学中的应用:利用分子生物学技术改造或生产动物性营养物质;从基因水平上研究如何提高动物生产性能及肉用性能:如肉质与瘦肉率等;在分子水平上研究营养与基因表达、调控的关系,以从根本上阐明营养对机体的作用机制;利用基因工程技术开发饲料资源。 Withthedevelopmentandtheapplicationof molecularbiotechnology,itis defussingintoallof lifefield,and penetratingintoeverybiologystudy.itis thetrendto explainthemodulationof nutrientto animalphysicalandpathological change.Themolecularbiologicalmechanismof growthanddevelopment,metabolize,inheritandvariation,immunityand disease,allof theseproblemneedto be lucubrated.Thisreviewevaluatedlatestdevelopmentabouttheapplicationof molec-ularbiologyinanimalnutrition,includedimprovementandproducingnewanimalnutritionsubstance;therelationshipbe-tweennutritionandgeneexpressionmodulation;mechanismdevelopfeedresourcesusinggeneticengineering.
作者 张锐 欧阳红生 张光圣 吴东林
机构地区 湛江海洋大学现代生化中心 中国人民解放军军需大学基础部生物化学教研室
出处 《生物技术通讯》 CAS 2002年第1期83-86,共4页 Letters in Biotechnology
关键词 分子生物学技术 动物营养 基因表达调控 应用 发展前景 molecularbiotechnology animalnutrition geneexpressingandmodulation
分类号 S815 [农业科学—畜牧学] Q493 [生物学—生理学]
  • 相关文献

参考文献19

  • 1Svanberg E, Ohlsson C. rhIGF-I/IGFBP-3 complex, but not free rhIGF-I, supports muscle protein biosynthesis in rats during semistarvation[J]. J Clin Invest, 2000,30(5):438
  • 2Fiorotto ML. Regulation of myofibrillar protein turnover during maturation in normal and undernourished rat pups[J]. J Physiol Regul Iutegr Comp Physiol,2000. 278(4):R845
  • 3Bonnet M. Lipoprotein lipase activity and mRNA are up-regulated by refeeding in adipose tissue and cardiac muscle ofsheep[J]. J Nut, 2000,130(4):749
  • 4Chapman C. Maternal and early dietary fatty acid intake: changes in lipid metabolism and liver enzymes in adult rats[J]. J Nutr,2000,130(2):146
  • 5Yin L, Zhang Y. Thyroid hormone glucagon, and medium-chain fatty acids regulate transcription I itiated from promoter I and promoter 2 of the acetyI-CoA carboxylase-alpha gene in chick embryo hepatocytes [J].J Biochim Biophys Acta,2000, 1517(1):91
  • 6Rhoads RP. Nutritional regulation of the genes encoding the acid-labile subunit and other components of the circulating insulin-like growth factor system in the sheep[J]. J Anim Sc ,2000, 78(10):2681
  • 7Ehrhardt RA. Development of a specific radioimmunoassay to measure physiological changes of circulating leptin in cattle and sheep[J]. J Endocrinol, 2000,166(3):519
  • 8Diener AC. Sterol methyltransferase I controls the level of cholesterol in plants[J]. Plant Cell, 2000,12(6):853
  • 9Fiorotto ML. Regulation of myofibrillar protein turnover during maturation in normal and undernourished rat pups[J]. Am J Physiol Regul Integr Comp Physiol, 2000,278(4):R845
  • 10Wray-Cahen CD. Redefining body composition: nutrients hormones,and genes in meat production[J]. Annu Rev Nutr, 1998,18:63

二级参考文献32

  • 1[1]Ahima R S et al. 1996. Role of leptin in the neuroendocrine response to fasting[J]. Nature, 382:250～252.
  • 2[2]Bjorbaek C, Uotani S,da Silva B, Flier J S. 1997. Divergent signaling capacities of the long and short isoforms of the leptin receptor [ J ]. J Biol. Chem., 272: 32686～32695.
  • 3[3]Borstein S R et al. 1997. Evidence for a novel peripheral action of leptin as a metabolic signal to the adrenal gland. Leptin inhibits cortisol release directly[J]. Diabetes, 46: 1235～1238.
  • 4[4]Campfield L A et al. 1995. Recombinant mouse OB protein: Evidence for a peripheral signal linking adiposity and central neural networks [ J ]. Science ( Wash DC), 269: 546 ～549.
  • 5[5]Carro J F et al. 1997. Regulation of in vivo growth hormone secretion by leptin[J ]. Endocrinology, 138:2203～2206.
  • 6[6]Chehab F F et al. 1997. Early inset of reproductive function in normal female mice treated with leptin[J]. Science, 275:88～90.
  • 7[7]Cohen S L et al. 1996. Characterization of endogenous human leptin[J ]. Nature, 382:589.
  • 8[8]Coleman D L. 1978. Obese and Diabetes: two mutant genes causing diabetes- obesity syndromes in mice[J].Diabetologia,14: 141～148.
  • 9[9]Coleman D L. 1973. Effects of parabiosis of obese with diabetes and normal mice [J ]. Diabetologia, 9:294～298.
  • 10[10]Cusin I et al. 1995. The ob gene and insulin A relationship leading to clues to the understanding of obesity[J ]. Diabetes, 44: 1467～1470.

共引文献8

同被引文献89

  • 1李宏,周庆安,刘文刚.mRNA差异显示技术、PCR技术及其在动物营养研究中的运用[J].饲料工业,2005,26(12):39-41. 被引量：3
  • 2涂勇刚,曹正辉,葛长荣.营养素调控与基因表达[J].云南农业大学学报,2005,20(5):605-608. 被引量：6
  • 3邵碧英,杨婕,张体银.动物产品的DNA提取方法[J].畜牧与兽医,2005,37(9):47-49. 被引量：28
  • 4李思经.生物技术发展的现状和展望[J].生物工程进展,1997,17(1):48-51. 被引量：20
  • 5Austin L G, Edwards A P. Metabolic regulation of gene transcription[J]. J Nutrition, 1994,124:1533-1539.
  • 6Weller P A, Daunceymj, Bates P C. Regulation of porcine insulin like growth factor and growth hormone receptor mRNA expression by energy status[J]. Am J Physiol, 1994,266:776-785.
  • 7Rhoads R P1. Nutritional regulation of the genes encoding the acid labile subunit and other components of the circulating insulin like growth factor system in the sheep[J]. J Anim Sci, 2000,78:2681-2687.
  • 8李德发.营养调控肉品质量的研究现状及发展趋势[M].动物营养研究进展,2004,7-14.
  • 9Bruhata,Fafournouxp.Recent advance on molecular mechanisms in-volved in aminoacid control of gene expression[J].Curr Opin Clin NutrMetab Care,2001(4):439-443.
  • 10Guan James Wu,Guo Jane Tsai.Chitooligosaccharides in combinationwith interferon-c increase nitric oxide production via nuclear factor-κB activation in murine RAW264.7 macrophages[J].Food and Chemi-cal Toxicology,2007,45:250-258.

引证文献6

二级引证文献7

生物技术通讯
2002年 第1期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部