C反应蛋白和儿科感染性疾病

C-reactive Protein and the Infections Disease in Children

目的 鉴别诊断儿童细菌 ,支原体感染和病毒感染。方法 免疫透射浊度法测定血清或血浆CRP值。结果 细菌 ,支原体感染CRP值基本 >8mg/L ,病毒感染CRP值基本 <8mg/L ;对与临床诊断不符的病例作动态分析 ,康复前后差别显著的以细菌或支原体感染为主 ,而差别不显著的以病毒感染为主。新生儿病人CRP值总体不高 ,以 8mg/L为判断界限来鉴别诊断较为困难。 结论 CRP的监测及动态分析对鉴别细菌 ,支原体感染和病毒感染有显著的临床意义 ,对新生儿病例不能以 8mg/L为判断界限 ,最好作动态分析。

Objective To discriminatingly analyse bacterial infection,Mycoplasma Pneumoniae or virus.Methods C-reactive protein (CRP) value in plasma or serum was measured by using immunoturbidimetic techniques.Result The level of CRP in bacterial or M.pneumoniae infection surpassed 8mg/L basically.In virus,however,it was below 8mg/L,but there were some values of specimens which was not in conformity with the clinical diagnosis were analysed dynamically.The patients for whom there were significant difference between phases of pre-and post-recovery were mainly infected by bacteria or myocplasma,while for those there were no singificant difference by virus mainly.We found that CRP value was not high as a whole in infant patients.It was difficult to use the value of 8mg/L to perform differential diagnosis.Conclusion CRP measurement and dynamic analysis have great significance to diagnose bacteria infection and M.pneumonial or virus clinically,but for infant patients we can not use the value of 8mg/L as a differential diagnosis criterion,the best way is dynamic analysis.