紫外线自血回输疗法对视网膜色素变性的治疗作用

Effect of ultraviolet blood irradiation on the treatment of retinitis pigmentosa

目的探讨紫外线照射自血回输疗法（ＵＢＩ）治疗视网膜色素变性（ＲＰ）的效果及机制。方法采用ＵＢＩ治疗ＲＰ患者４０例８０眼，观察治疗１个疗程前后视力、视野敏感度阈值（ＭＳ），扫描电镜红细胞形态及血液流变学改变。并随访坚持治疗６个疗程的患者１５例３０眼。结果经１个疗程治疗后，患者视力明显提高，视野改善，正常ＲＢＣ数量明显高于治疗前且与健康人无差异，全血高切、低切比黏度、红细胞压积、红细胞聚集性均降低，而血浆比黏度无明显改变。治疗６个疗程后视力、视野较治疗１个疗程时有所提高。结论ＵＢＩ具有提高红细胞变形能力，降低血黏度从而改善微循环的作用，是治疗ＲＰ的一种较有效的方法。

ObjectiveTo determine the effect and mechanism of ultraviolet blood irradiation(UBI) on the treatment of retinitis pigmentosa.MethodsFourty patients with retinitis pigmentosa were treated with UBI.The visual acuity,MS,RBC morphology and the hemorheology before and after treatment were compared.ResultsBy UBI treatment, the visual acuities of the patients and the visual field improved.The amount of normal RBC was increased and similar to that of normal person.The blood viscosity and hematocrit were decreased while the viscosity of plasma was not changed markedly.After 6 courses of treatment,the visual acuities and the visual field of patients were more improvedConclusionUBI therapy can promote mobility of RBC and decrease the blood viscosity,then improve the microcirculation. UBI might be an effective therapy for retinitis pigmentosa.