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琼脂凝胶键连热聚IgG——一种新型类风湿关节炎免疫吸附剂 被引量:1

HEAT-AGGREGATED IgG LINKED TO AGAR GEL A NEW IMMUNOADSORBENT FOR RHEUMATOID ARTHRITIS
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摘要 将热聚IgG固载到琼脂凝胶珠上 ,制成了一种特异性类风湿关节炎免疫吸附剂。体外吸附实验表明该吸附剂对类风湿因子及其免疫复合物具有强的选择吸附性能 。 A new immunoadsorbent for rheumatoid arthritis was developed by binding heat aggregated human IgG to agar gel beads. Experimental results showed that the adsorbent had a high affinity to RF and IC. Furthermore, it possessed fine stability and blood compatibility, its mechanical strength was suitable for hemoperfusion. These properties of the adsorbent showed its potential applications in clinic medicine.
出处 《中国生物医学工程学报》 CAS CSCD 北大核心 2002年第1期1-4,共4页 Chinese Journal of Biomedical Engineering
基金 国家 8 63项目资助课题 (863 715 0 0 2 0 191)
关键词 类风湿关节炎 类风湿因子 免疫吸附剂 热聚IgG 琼脂凝胶珠 Rheumatoid arthritis Rheumatoid factors Immunoadsorbent Heat aggregated human IgG
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