摘要
肽核酸 (PNA)是一类人工合成的核酸类似物 ,PNA与核酸链以 Waston- Crick碱基配对方式稳定互补结合 ,具有高度的亲合性、稳定性、特异性特征 ,PNA能调节基因的表达作用 ,包括调节基因的复制、转录 (或逆转录 )、翻译过程 ,因此 PNA有着广泛的分子生物学效应 。
Peptide nucleic acid (PNA) is a kind of artificial DNA mimic. PNA hybridizes with DNA or RNA by means of Waston Cricks base pairs complementary with high stability, affinity and selectivity. PNA not only regulates DNA replication, but also adjusts DNA transcription (or reverse transcription) and translation. Many applications have been explored as a new kind of molecular biological tool and a gene targeting strategy.
出处
《动物科学与动物医学》
2002年第1期9-12,共4页
Animal Science & Veterinary Medicine
