血糖浓度变化与消化间期综合肌电周期的关系

THE RELATIONSHIP BETWEEN CHANGE IN CONCENTRATION OF BLOOD SUGAR AND PERIOD OF INTERDIGESTIVE MYOELECTRIC COMPLEX

在狗的十二指肠浆膜面埋植银-氯化银双极电极,记录空腹时的肌电活动,观察血糖浓度变化与消化间期综合肌电(IDMEC)周期的关系。实验结果表明:(1)血糖浓度随 IDMEC周期的不同时相而变动,Ⅰ相最高,Ⅱ相次之,Ⅲ相最低(P<0.01)。(2)静脉注射酚妥拉明或心得安后。血糖浓度随 IDMEC 周期的波动均消失。(3)切除双侧迷走神经干后,血糖浓度略有升高,随 IDMEC 的周期性波动依然存在。(4)分别阻断肾上腺素α、β受体及切除迷走神经后,不影响 IDMEC 的周期性活动,但可使周期延长,各相所占时程百分比发生变化。以上结果证明,空腹情况下血糖浓度随 IDMEC 周期的不同时相而变动,交感神经和迷走神经具有一定的调节作用。

We studied the relationship between changes in blood sugar level and periodsof interdigestive myoelectric complex(IDMEC)in dogs,and found that the bloodsugar concentration varied in each phase of IDMEC cycles,being the highest inphase I and the lowest in phase Ⅲ.After intravenous injection of phentolamineor propranolol,the cyclic fluctuation of blood sugar level was abolished but theduodenal IDMEC still peisisted.After vagotomy,blood sugar concentration washigher than that in fasting dogs and still showed fluctuations in the IDMEC cycle.