喷雾法制备固定化酶载体——磁性聚丙烯腈微球

Preparation of Carrier of Enzyme-immobilization-magnetic Polyacrylonitrile Microsphere by Spray Method

介绍了一种制备磁性聚丙烯腈微球的方法。将纳米磁粉均匀分散于聚丙烯腈的 N,N-二甲基甲酰胺溶液中 ,用喷雾法制备了具有超顺磁性的聚丙烯腈微球 ,并对微球制备过程中的影响因素进行了综合考察。得到了粒度分布在 1 .0 μm～ 1 .5 μm、磁含量约为 1 5 %的磁性聚丙烯腈微球 ,其最佳制备条件为 :以 N,N-二甲基甲酰胺为溶剂 ,CPAN=1 g/ L,T=1 80℃ ,n=30 0 0 0 r/ min,V=2 m L/ s,Cmagnetic fluid=2 g/

A new method of the preparation of carrier of enzyme immobilization magnetic polyacrylonitrile microsphere was reported in this paper. Dispersed the nanometer magnetic fluid into the N,N dimethylformamide solution of polyacrylonitrile, the suparamagnetic polyacrylonitrile microsphere was obtained by using spray method. The influence factor on the particle properties were investigated in detail. Under the optimum conditions: C PAN =1g/L, T =180℃, n =30 000r/min, V =2mL/s, C magnetic fluid =2g/L, suparamagnetic polyacrylonitrile microspheres with narrow disperse(1.0μm～1.5μm) were prepared.