长春地区泌尿生殖道感染者解脲支原体血清分型研究

A study on serotypes of U. urealyticum isolated from patients with urogenital infections in Changchun area

目的 :了解长春地区解脲支原体 ( UU)所致泌尿生殖道感染现状及各血清型在不同人群中的分布情况。方法 :采用 UU的 1 4个标准分型血清对长春地区 1 84例 UU感染的阳性分离株应用代谢抑制实验方法进行血清分型鉴定。结果 :不同组别的 UU优势血清型不同 ,有泌尿生殖道感染症状 (显性感染 )组的 UU优势血清型为 4、3、8、1型 ;无泌尿生殖道感染症状 (隐性感染 )组的UU优势血清型为 3、6、1 4、4型。UU的 4、8型在显性感染组中的阳性分离率显著高于隐性感染( P<0 .0 5 )。未定型 UU在显性感染组中检出 8例 ,在隐性感染组中未检出。结论 :长春地区的 4、8型 UU与显性感染有密切的相关性 ;3、6、1 4型的

Objective:To investigate urogenital infections with U.urealyticum(UU)isolated from patients with STD and the distribution of serotypes in different populations in Changchun area. Methods:184 UU islates was identified by 14 standard UU typing antisera in metabolism inhibition test.Results:Variety of patient groups has distinct preponderant serotypes in inapparent infection patient group:in group of patients with urogenital infectious symptoms preporderant serotypes was 4?3?8 and 1,respectively,according their frequency. However,in group of patients without symptoms preponderant serotypes was 3?6?14 and 4,respectively. Isolation rate of UU serotype 4 and 8 was remarkably higher in aparent infection group than that of inapparent infection group; 8 strains of untyping UU was isolated in apparent infection group.Conclusion:In Changchun area, both UU serotype 4 and 8 is associated with apparent infection,whereas 3, 6 and 14 are major colonizational strains; Multi serotypes and untyping UU infections are closely related to sexually promiscuous behaviour.