cTnⅠ与CK-MB对AMI诊断价值的研究

Comparison study of cardiac troponinⅠ and creaine kinase-MB on acute m yocardial infarction

目的 :研究比较心肌肌钙蛋白 与肌酸激酶同工酶对急性心肌梗死的诊断价值。方法 :急性心肌梗死 (AMI)患者 45例 ,不稳定型心绞痛 (U AP)患者 42例 ,陈旧性心肌梗死 (OMI)患者 47例 ,检测其血清中的肌钙蛋白 (c Tn )和肌酸激酶同工酶 (CK-MB) ,对比观察三组患者的检测结果。结果 :AMI组 c Tn 检测为阳性结果的例数明显高于 UAP组及OMI组 (P<0 .0 1)。 c Tn 诊断 A MI的敏感性为 10 0 % (4 5 / 45 ) ,CK -MB为 86.7% (3 9/ 45 ) ;c Tn 诊断 AMI的特异性为96.7% (86/ 89) ,CK-MB为 5 5 .1% (4 9/ 89)。c Tn 检测的敏感性和特异性均明显高于 CK-MB。结论 :c Tn 对于诊断A MI较 CK-MB具有更高的敏感性和特异性 ,且检测更方便、快捷 ,对 AMI的诊断、鉴别诊断等具有重要意义 ,是一种新的更有价值的

Objective:It is to com pare and research the diagnosis value of cardiac troponin (c Tn ) and creaine kinase-MB(CK-MB) on acute myocardial infarction.Methods:Forty-five acute myocardial infarction patients were in A MI group.Forty-two unstable angina pectoris patients were in UAP group.Forty-seven obsolete m yocardial infarction patients were in OMI group.The c Tn and CK-MB in serum of the above three groups were exam ined,and different examined results were com pared and observed.Results:The positive cases in AMI group were m ore than those in U AP group and OMI group (P<0 .0 1) .The sensitivity of AMI diagnosed with c Tn was 10 0 % (4 5 /4 5 ) and thatwith CK-MB was 86. 7% (3 9/4 5 ) .The idiosyncrasy of AMI diagnosed with c Tn was96.7% (86/89) and that with CK-MB was5 5 .1% (4 9/ 89) .The sensitivity and idiosyncrasy of exam ination with c Tn were higher than that with CK-MB.Conclusion:The c Tn is much m ore sensitivity and idiosyncrasy than CK-MB on diagnosis of AMI,and it is m uch m ore convenient and quickly. The c Tn is a new and m ore valuable idiosyncrasy sign on diagnosis of AMI.