摘要
目的 探讨动脉粥样硬化斑块与肾素血管紧张素系统 (RAS)和纤溶系统之间的关系。方法 根据超声检查和冠状动脉造影将 78例受试者分为正常组 (A组 )和动脉粥样硬化组 (B组 )。检测血浆血管紧张素Ⅱ、醛固酮、纤溶酶原激活物及纤溶酶原激活物抑制剂。结果 A组和B组AngII分别为 (3 2 .68± 13 .85 ) pg/ml和 (3 6.96± 3 0 .2 )pg/ml,Ald分别为(0 .2 1± 0 .0 6) pg/ml和 (0 .2 4± 0 .0 4) pg/ml ,PAI 1分别为 (0 .5 1± 0 .17)AU/ml和 (0 .5 9± 0 .14 )AU/ml ,两组测值均存在显著性差异 (P <0 .0 5 ) ;t PA分别为 (0 .3 3± 0 .12 )IU /ml和 (0 .3 5± 0 .15 )IU /ml(P >0 .0 5 )。结论 动脉粥样硬化斑块形成患者血液中的RAS和纤溶系统分泌异常。
Objective To explore the relationship between the atherosclerosis and renin angiotension system or fibrinolysis system. Methods The association between plasma levels of angiotension II (AngII), aldosterone (Ald),tissue plasminogen activator (t PA),or plasminogen activator inhibitor type 1 (PAI 1) were investigated. Results The plasma levels of AngII, Ald and PAI 1 were significantly higher in group B than those of group A ( P <0.05). There was no significant difference in t PA between the two groups ( P >0.05). Conclusion The patients with atherosclerotic plaque exist abnormality of function of renin angiotension system or fibrinolysis system.
出处
《中国医学影像技术》
CSCD
2002年第1期49-50,共2页
Chinese Journal of Medical Imaging Technology
基金
卫生部优秀青年人才专项基金资助 (970 37)
