采用羊膜移植行结膜囊成形术的临床研究

Clincal study of reconstructing anophthalmia conjunctival sac with amniotic membrane transplantation

目的 评价保存人羊膜移植在结膜囊成形术中的疗效。方法 31例无眼球结膜囊狭窄患者行结膜囊成形术时 ,结膜缺损用羊膜移植。结果 术后 2 2～ 30天移植的羊膜被结膜上皮覆盖 ,随访 12～ 36个月 ,无继发感染及排异反应 ,2 7例放置正常大小义眼片 ,外观满意 ,4例于术后 3～ 5个月出现结膜囊收缩。结论 保存人羊膜移植治疗结膜囊缩窄取材方便 。

Objective To evaluate the effect of amniotic membrane transplantation for reconstructing conjunctival sac. Methods 31 patients suffered conjunctival sac constriction were treated with amniotic membrane transplantation. Results Areas of implanted amniotic membrane were entirely covered by epithelium at 22～30 days postoperatively. No secondary infection and rejection were persent in 12～36 months of follow up. 27 of the 31 patients were able to wear an ocular prosthesis comfortably. Cosmesis was acceptable. Four patients had recurrent conjunctival sac contracture 3～5 months postoperatively. Conclusion The amniotic membrane has the characteristics of no antigenicity and are easy to obtain. The transplantation of preserved amniotic membrane is a valuable method for the treatment of anophthalmia conjunctival sac constriction.