不同反应条件对非氰化钠路线合成巴丹的影响

The Effect on Synthesising Cartap by Route of Non-sodium Cyanide under the Difference Conditions of Reaction

以N ,N -二甲基 - 2 ,3-二氯丙胺为原料 ,与硫氰化钠反应 ,再经醇解制得产品巴丹 ,正构体含量为 97% ,收率为 5 4 5 %。同时对反应的 pH值、时间和温度作了研究。

The cartap was prepared by reaction of N,N-dimethyl-2,3-dichlor oaminopropane with sodium sulfocyanate then alcoholysis The purity of normal compound is 97% and yield is 54 5% The pH of medium , reactiontime and temperature were also discussed