翼状胬肉复发与组织病理学的关系

The relationship between the recurrence of pterygium and the histopathology

目的 :分析翼状胬肉复发与组织病理学的关系。方法 :选择连续、自愿接受平阳霉素注射并能按我院要求随访的患者 5 4例 ,62只眼 ,给予平阳霉素 8mg和地塞米松 5mg以生理盐水 1ml或 2ml稀释的平阳霉素地塞米松混合液抽 0 1～0 2ml翼状胬肉体部注射 ,6～ 9天后行翼状胬肉切除 +带蒂结膜瓣转位移植 +巩膜暴露术 ,胬肉组织送病理 ,跟踪 10～ 4 0个月 ,观察胬肉的复发率。结果 :复发的 6只眼中 5只眼病理结果均有不同程度的鳞状上皮增生 ,占 83 3 3 % ,而对于无复发者 ,鳞状上皮增生者仅占 8 93 %。结论 :翼状胬肉的复发与患者胬肉的组织病理关系密切 ,鳞状上皮增生者复发率相对较高 ,χ2检验P <0 0 0 5 。

Objective:To study the relationship between the recurrence of pterygium and the histopathology.Methods:Pterygia of 62 eyes(54 patients) were excised with autografting conjunctiva and exposure of sclera.6～9 days prior to the excision,a mixture(0 1～0 2 ml) of 5 mg DXM,8 mg pingyangmycin and 1～2 ml NS was injected subconjunctivally at pterygium.All excised specimens were examined pathologically.Patients were followed up for 10～36 months.Results:Proliferation of squamous epithelium was found in 83.33% of all recurrent pterygia,but only 8.93% in 56 nonrecurrent pterygia.The difference is significant statistically (P<0 005).Conclusion:Recurrence of pterygium is much related to the proliferation of squamous epithelium.