期刊文献+

术中放疗的吸收剂量测算方法的研究 被引量:1

Experimental study of dosimetry for intra-operative radiotherapy
原文传递
导出
摘要 目的 研究和比较水、固体水及有机玻璃 3种模体的术中放疗吸收剂量的测算方法。方法 对于 3种模体 ,使用固定在水模体中的电离室对加速器的电子束术中放疗限光筒进行吸收剂量的测算 ,首先选定参考限光筒对所有能量的电子束在源皮距SSD =10 0cm ,水模内射束中心轴上特定深度 ,通过调整加速器使 1cGy =1MU ,然后使用术中放疗及参考限光筒在相同的辐照条件下进行测量 ,即测量术中放疗限光筒的输出因数。对于水模体 ,计算出各限光筒的吸收剂量cGy对应的加速器输出MU数值。并据此计算出固体水模体和有机玻璃模体的各限光筒吸收剂量cGy对应的加速器输出的MU数值。结果 相对于水模体 ,有机玻璃模体的测量误差为 0 2 7%。固体水为0 45 %。 Objective\ To study and compare the dosimetry for intra operative radiotherapy in three kinds of phantoms;water,solid water and polymethyl ones. Methods\ The absorbed dose from electrons of the accelerator with the applicator for intra operative radiotherapy was measured using an ionization chamber fixed on each phantom.The dose at the specific depth in water on the beam central axis was adjusted to 1 cGy per monitor unit for the reference applicator with SSD at 100 cm for all energy levels of electrons.Then the applicator for intra operative radiotherapy was used with no other change,i.e.the output factor was measurd.The values of MU per cGy absorbed dose for all applictors in water phantom were calculated,and these values were used to calculate the MU value per cGy absorbed dose from the output factors for solid and polymethyl phantoms. Results\ The deviation from water phantom was 0.27% and 0.45% for polymethyl and solid water ones,respectively. Conclusion\ Using a polymethyl phantom to measure the absorbed dose may be a practical method when no special water tank or solid water is available.
出处 《中华放射医学与防护杂志》 CAS CSCD 北大核心 2001年第5期371-374,共4页 Chinese Journal of Radiological Medicine and Protection
关键词 术中放疗 剂量测量方法 模体 肿瘤 放射疗法 Intra\|operative radio therapy(IORT) Dosimetry Phantoms
  • 相关文献

参考文献4

  • 1曾狄闻 陈国雄 等.现代肿瘤术中放射治疗学[M].北京:人民军医出版社,1996.50-76.
  • 2胡逸民,肿瘤放射物理学,1999年,149页
  • 3冯宁远,实用放射治疗物理学,1998年,111页
  • 4曾狄闻,现代肿瘤术中放射治疗学,1996年,50页

共引文献4

同被引文献16

  • 1Veronesi U, Oreechia R, Luini A, et al. Intraoperative radiothera- py during breast conserving surgery:a study on 1,822 cases treated with electrons [ J ]. Breast Cancer Res Treat, 2010,124 ( 1 ) : 141 - 151. DOI : 10. 1007/s10549-010-1115-5.
  • 2Holmes DR, Baum M, Joseph D. The TARGIT trlal: targeted intr- aoperative radiation therapy versus conventional postoperative whole-breast radiotherapy after breast conserving surgery for the management of early-stage invasive breast cancer ( a trial up-date)[J]. Am J Surg,2007,194(4) :507-510.
  • 3Vaidya JS, Josepo DJ, Tobias JS,et al. Targeted intraoperaUve ra- diotherapy versus whole breast radiotherapy for breast cancer ( TARGIT-A trial ) : an international, prospective, randomized, non-inferiority phase 3 trial [ J ]. Lancet, 2010,376 ( 9735 ) : 91- 102.1301,10. 1016/S0140-6736 (10) 60837-9.
  • 4Ahnesjo A, Aspradakis MM. Dose calculations for external photon beams in radiotherapy [J]. Phys Med Biol, 1999,44 ( 11 ) :99- 155.
  • 5Kuerer HM, Julian TB, Strom EA, et al. Accelerated partial breast irradiation after conservative surgery for breast eaneer [ J]. Ann Surg,2004,239 ( 3 ) :338-351.
  • 6Vemnesi U, Oreeehia R, Luini A, et al. Full-dose intraoperative radiotherapy with electrons during breast conserving surgery:expe- rience with 590 Cases [ J]. Ann Surg,2005,242( 1 ) : 101-106.
  • 7Lemanski C, Azria D, Gourgon-Bourgade S, et al. lntraoperative radiotherapy in early-stage breast cancer: results of the montpellier phase I] trial [J]. Int J Radiat Oncol Biol Phys,2010,76(3) : 698-703. DOI:10. 1016/j. ijrobp. 2009.02. 039.
  • 8Veronesi U, Orrechia R, Luini A, et al. A preliminary report of intraoperative radiotherapy IORT in limited stage breast cancers that are conservatively treated [ J]. Eur J Cancer,2001,37 (17) : 2178-2183.
  • 9Krans-Tiefenbacher U, Schfda A, Steil V,et al. Intraoperative ra- diotherapy (IORT) for breast cancer using the intrabeam system [ J]. Tumori ,2005,91 (4) :339-345.
  • 10Bernard D, Chu JC, Rozenfeld M, et al. Design optimization of in- traoperative radiotherapy cones [J]. Inter J Radiat Oncol Biol Phys,2005,55 (5) : 1446-1457.

引证文献1

二级引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部