口腔矫治器治疗阻塞性睡眠呼吸暂停综合征

Clinical effect of oral appliance in the treatmeat of obstructive sleep apnea syndrome

目的 探讨口腔矫治器对阻塞性睡眠呼吸暂停综合征 (OSAS)患者的临床疗效。方法 将 3 2例OSAS患者分为轻中度组和重度组 ,分别制作“下颌前移型”口腔矫治器并在睡眠时配戴 ,用多导睡眠图监测患者治疗前后睡眠结构及呼吸功能的变化。结果 使用口腔矫治器后轻中度组和重度组患者的呼吸暂停指数 (AI)分别平均下降 11.3次 /小时 ( P <0 .0 0 1)和 2 6.0 1次 /小时 ( P <0 .0 0 1) ,最低SaO2 分别平均升高 3 .65 % ( P <0 .0 1)和19.75秒 (P <0 .0 5 )。

Objective To explore the effect of the oral appliance for the treatment of obstructive sleep apnea syndrome(OSAS).Methods 32 cases were divided into light-middle group and serious group.Patients of the two groups were separately requested to put on the oral appliance when sleeping.Polysomnography(PSG) was used to monitor the effect of the oral appliance on sleep and respiratory conditions before and after treatment.Results Through oral appliance therapy,the average AI of the light-middle group and serious group patients decreased by 11.53 events per hour(P< 0.001 )and 26.01 events per hour (P< 0.001 ),the lowest SaO 2 value increased 3.65 %(P< 0.001 )and 12.51 %(P< 0.001 ),the longest apnea time was shortened by 26.55 seconds(P< 0.001 )and 19.75 seconds(P< 0.05 ).Conclusion The oral appliance is an effective method for the treatment of OSAS.