黄烷类化合物研究(Ⅱ)——(±)-4'-羟基-5,7,3'-三甲氧基黄烷和(±)-5,4'-二羟基-7,3'-二甲氧基黄烷的全合成

Studies on Flavans(Ⅱ) ——Total Synthesis of 4'-Hydroxy-5,7,3'-trimethoxyflavan and 5,4'-Dihydroxy-7,3'-dimethoxy Flavan

以 2 ,4 ,6-三羟基苯乙酮和香草醛为起始原料 ,经选择性甲基化、甲氧甲基化、缩合、关环和脱羰基等步骤首次完成了 (± ) 4 -羟基 -5 ,7,3 -三甲氧基黄烷和 (± ) -5 ,4 -二羟基 -7,3

Hydroxy 5,7,3 trimethoxyflavan and 5,4 dihydroxy 7,3 dimethoxyflavan were first synthesized by selective methylation, methoxymethylation, condensation, cyclization, deoxygenation from 2,4,6 trihydroxyacetophone and vanillin.