苯酚胶浆女性粘堵绝育术后输卵管超微结构观察

Ultrastructural Study of Female Fallopian Tubes After the Occlusive Sterilization with Phenol-Mucilage

本文收集了10例女性苯酚胶浆粘堵绝育术后1～7年行复通术时切下的输卵管组织,进行透射电镜观察,所见输卵管闭塞部位主要为大量胶原纤维,少量的纤维细胞和散在的淋巴细胞,邻近闭塞部位的输卵管粘膜上皮显示单层排列的纤毛细胞和分泌细胞。上述细胞的形态和超微结构未见病理改变。这10例受术者在复通术后1年内有5人怀孕。结果表明苯酚胶浆粘堵绝育时间长久后对输卵管组织无恶性变影响,提示这种绝育方法的远期安全性是比较可靠的。1例输卵管粘膜见到细菌,这一发现值得注意。

Tubal biopsy specimens were obtained at the time of tubal reversal operation in 10women who had had occlusive sterilization by phenol-mucilage,the interval betweensterilization to reversal operation ranged from 1 to 7 years.Transmission electronmicroscopy revealed that at the site of the tubal occlusion was abundant collagen fibrils,a few fibrocytes and scattered lymphocytes.The mucosal epithelium adjacent to the tubalocclusion showed simple columnar ciliated cells and secretory cells.No pathological changesor all these cells were seen. Five of the ten patients had become pregnant after one yearfollowing reversal operation.Our evidence suggests that the occlusive sterilization withphenol-mucilage does not induce anv malignant changes on tubal tissues even after a longtime.It is indicated that this method of sterilization is safe.However bacteria were foundin one mucosal epithelal specimen.Attention should be paid to this observation.