持续微导管引流及胸腔内药物治疗恶性胸水

Continuous Drainage with Microcatheter and Intrathoracic Cavity Drug Therapy for Malignant Pleural Effusion

目的：应用榄香烯乳液治疗恶性胸腔积液，旨在观察临床疗效和毒副作用。方法：采用持续微导管引流法，对40例患者行榄香烯乳液胸腔内注入。结果：恶性胸水控制率为85．0％，腔内注药后出现发热、恶心、呕吐及胸痛不良反应，经对症处理可以缓解。结论：持续微导管引流胸液后腔内注药的方法方便、安全，值得在临床上推广应用。榄香烯乳液是一种控制恶性胸水的有效药物。

Objective： To study the drug action of elemene emulsion and its adverse reaction in treatment of malignant pleural effusion． Methods： A new technique of microcatheter drainage was used in 20 cases of malignant pleural effusion treated with elemene emulsion of 400mg＋100ml normal saline injected intrathoracically． Results： The control rate of malignant effusion was 85％ (17／20)． The side effects of pyrexia， chest pain， nausea and vomiting were seen in some patients and it could be relieved by symptomatic treatment． Conclusion： Continuous microcather drainage and intrathoracic elemene emulsion injection is a convenient， safe method for treatment of malignant pleural effusion and it can be widely used．