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NF-κB拮抗措施的研究进展 被引量:3

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摘要 核因子 κB(NF κB)是一种重要的转录调节因子 ,NF κB过度激活与多种疾病有关。因此 ,针对NF κB激活途径中的不同环节为靶点进行拮抗 ,可以治疗与之相关的疾病。本文就近年来抑制NF κB活化的拮抗措施作一简要综述。
出处 《国外医学(生理病理科学与临床分册)》 2001年第6期456-459,共4页 Foreign Medical Sciences(Pathophysiology and Clinical Medicine)
基金 国家973重点基础研究项目 :G19990 5 42 0 3
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  • 1Chen F,Casteravova V,Shi X, et al . Clin Chem, 1999,45(1):17-17.
  • 2Lee JI, Pharmd D, Burckart GJ, et al.J Clin Pharmacol, 1998,38:981-993.
  • 3Imbert V,Rupec RA,LivolsiA, et al. Cell, 1996,86:787-798.
  • 4Bowie A, O'Neill LAJ. Biochem Pharmacol,2000,59:13-24.
  • 5Rossi A, Kapahi P, Natoli G, et al . Nature, 2000,403(6):103-108.
  • 6May MJ, D'AcquistoF , Madge LA, et al . Science , 2000, 289 :1550-1554.
  • 7MengL, MohanR, Kwork BHB. Proc Natl Acad Sic, 1999,96(18):10403-10408.
  • 8Yama IC. Exp Neurol, 1999,57(2):359-365.
  • 9Stublmeier KM,Kao JJ,Bach FH, et al . J Biol Chem, 1997,272(39):24679-24683.
  • 10SawaY, Morishita R, Suzuki K, et al . Circulation, 1997,96:280-285.

同被引文献49

  • 1许建英,徐永健.NF-κB在肺部炎症性疾病中的作用[J].国外医学(内科学分册),2002,29(2):60-63. 被引量:5
  • 2[1]Sokoloski JA,Shyam K,Sartorelli AC.Induction of the differentiation of HL-60 promyelocytic leukemia cells by curcumin in combination with low levels of vitamin D3[J].Oncol Res,1997,9:31-39.
  • 3[2]Mitchell BS.The proteasome-An emerging therapeutic target in cancer[J].N Engl J Med,2003,348 (26):2597-2598.
  • 4[3]Arsura M,Wu M,Sonenshein GE.TGF betalinhibits NF-kappa B/Rel activity inducing apoptosis of B cells:transcriptional activation of I kappa B alpha[J].Immunity,1996,5 (1):31-40.
  • 5[4]D' Acquisto F,May MJ,Ghosh S.Inhibition of nuclear factor kappakB (NF-κB):An emerging theme in anti-inflammatory therapies[J].Mol Inter,2002,2(1):22-35
  • 6[5]Garg A,Aggarwal BB.Nuclear transcription factor-κB as a target for cancer drug development[J].Leukemia,2002,16 (6):1053-1068.
  • 7[6]Bharti AC,Aggarwal BB.Nuclear factor-kappa B and cancer:its role in prevention and therapy[J].Biochem Pharmacol,2002,64(5-6):883-888.
  • 8[8]Karin A,Yamamoto Y,Wang M.The Ikk NF-κB system:a treasure trove for drug development[J].Nature Rev Drug Discov,2004,3 (1):17-26.
  • 9[1]Kiarash A, Pagano PT,Tayeh M, et al. Upregulated expression of rat heart intercellular adhesion molecular-1 in angiotensin Ⅱ-but not phenylephrine-induced hypertension[J].Hypertens,2001,37(1):58-65.
  • 10[3]Rothelein R,Mainoliti EA,Czajkawski M,et al A form of circulating ICAM-1 in human serum[J].J Immunol,1991,147(14):3788-3797.

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