不同提取工艺酸枣仁汤的药效学研究

Pharmacodynamics Study of Suanzaoren Decoction Extracted by different Technological Processes

目的:通过药效学研究对酸枣仁汤剂提取工艺进行筛选。方法:观察不同提取工艺样品对小鼠自主活动和对阈上剂量戊巴比妥钠所致睡眠时间的影响。结果:酸枣仁汤水煎液和95％醇提液均有镇静、催眠作用。结论:选取酸枣仁汤水煎液为较优提取工艺。

Objective: To select the optimal technological process for Suanzaoren decoction. Method: The effects of extracts from different technological processes on spontaneous motion and sleep time in mice induced by pentobarbital sodium (subthreshold dosage) were studied. Results: Both the decoction and 95% alcohol extract of Suanzaoren possess sedative and hypnotic effects. Conclusion: Suanzaoren aqueous decoction was selected as the optimal technological process.