万古霉素治疗新生儿重症感染性肺炎对照试验

A Controlled Experiment of Vancomycin in Treatment of Neonate with Severe Infectious Pneumonia

目的 :观察万古霉素治疗新生儿重症感染性肺炎的临床疗效及安全性。方法 :随机将 32例新生儿感染性肺炎分为治疗组 (万古霉素 )和对照组 (第三代头孢菌素 )。结果 :万古霉素治疗新生儿重症葡萄球菌感染性肺炎的总有效率 87.5 % ,明显高于对照组 (5 0 .0 % ) ,不良反应少。结论 :万古霉素治疗新生儿葡萄球菌肺炎疗效肯定 ,安全可靠。

Objective: To observe clinical therapeutical effect and safety of vancomycin in treatment of neonate with severe infectious pneumonia. Method: 32 cases, who were ill with infectious pneumonia, were randomly divided treated group(vancomycin) and controlled group(third generation cephalosporin). Results:The total effetive rate of vancomycin in treatment of neonate with severe infectious pneumonia due to staphylococci was 87.5%, which was obviows higher than the controtled group. The adverse reactions in the treated group was few. Conclusion: The therapeutical effect of vancomycin in treatment of neonate with staphylococcal pneumonia is defenite and safe.