声学密度定量技术评价梗死心肌的收缩能力

Quantitative ultrasonic evaluation of myocardial contractility in infarction by acoustic densitometry

目的 探讨声学密度定量技术 (AD)定量评价梗死心肌收缩能力的临床价值。方法 检测 5 9例各期心肌梗死患者梗死心肌及 2 0例对照者正常心肌背向散射积分参数以及相应部位心肌收缩期室壁增厚率( ΔT %)和左室射血分数 (EF)。结果 梗死心肌背向散射积分参数与正常心肌相比差异均有显著性意义 ;心动周期变化幅度 (CVIB)及CVIB校正值 (CVIB %)与 ΔT %及EF均具有较高的相关性。结论 AD能够客观、敏感地反映梗死心肌的局部收缩能力 。

Objective To quantitatively access the myocardial contractility in infarction using acoustic densitometry(AD).Methods Some integrated backscatter parameters were measured in 59 patients with recent or old myocardial infarction (group 1) and 20 normal persons (group 2).Meanwhile percent systolic wall thickening (ΔT%) and ejected fraction of left ventricle (EF) were measured.Results There were significant difference in integrated backscatter parameters between group 1 and group 2; the magnitude of cyclic variation in integrated backscatter(CVIB) and the ratio of CVIB (CVIB%) had close correlation with ΔT% (r= 0.746, 0.756,P< 0.001),and the mean of CVIB and CVIB% had good correlation with EF (r= 0.685, 0.693,P< 0.01).Conclusions Acoustic densitometry can quantitatively detect the regional myocardial contractility.It is useful for the evaluation of the whole contractility of left ventricle.