摘要
目的 总结儿童颅内单发小炎性肉芽肿的临床特点和治疗经验。方法 自1997年1月~2001年6月手术治疗颅内单发小炎性肉芽肿患儿24例,占同期全年龄组颅内炎性肉芽肿总病例数的47.06%(24/51),平均年龄10.67岁,男女之比为2.4:1。症状以癫痫发作最为常见,占79.17%(19/24)。病灶分布以顶枕叶多见(50.00%),额叶次之(29.17%)。结果 非特异性肉芽肿14例,占58.33%,寄生虫性肉芽肿10例,占41.67%,二者周围组织水肿程度有所不同。病灶均经手术全切除,随访15例患儿均临床痊愈。结论 “小环形”强化病灶是颅内炎性肉芽肿的特征性表现,符合手术指征者,显微外科手术全切除是最佳的治疗选择。
Objective The clinical characteristics and therapeutic experiences of intracranial solitary small inflammatory granuloma in children were studied. Methods The clinical data of 24 patients operated during January 1997 to June 2001 were retrospectively analyzed. The patients' average age was 10.67 years old. The male/female ratio of these patients was 2.4:1. Seizure (19/24) was the most common symptom in the patients. Occipitoparietal lobe was the most common location (50.00%) of inflammatory granuloma, and frontal lobe (29.17%) took second place. In the same period, these patients reached 47.06% of all patients with intracranial inflammatory granuloma. Results Non-specific inflammatory granuloma reached 58.33%, and the rest cases were cysticerous granuloma, between the two groups, the edema extent was different from each other. After the total removal of lesion, most patients recovered clinically. Conclusion It is showed that the 'small ring' enhanced focus is the characteristic of intracranial inflammatory granuloma, and the mi-crosurgical total removal is the best therapeutic approach.