超声合成1-甲氧基-4-烷氧基苯

Supersonic Synthesis of 1-Methoxy-4-Alkoxybenze

以对甲氧基苯酚和H(CH2 ) nBr(n =4,6,8,9,10 )为原料 ,甲醇钠和甲醇为溶剂 ,在N2 保护下 ,用超声催化合成 1 甲氧基 4 烷氧基苯 ,反应 5h ,收率可达 89%。反应的适宜条件为 :MOPh和H(CH2 ) nBr摩尔比为 1∶1,甲醇钠的浓度为 2 .0mol·l-1(溶剂CH3 OH) ,超声频率 3 3±

Methoxy 4 alkoxybenzene was prepared from p methoxy phenol(MOPh)and H(CH 2) nBr under nitrogen in the supersonic waves.Sodium methoxide and methanol was solvent,The yield was 89%.The reaction conditions:mol ratio of MOPh/H(CH 2) nBr was 1,condensation of sodium methoxide was 2.0 mol·l -1 ,supersonic ratio was 33±2 kHz,reaction time was 6 h.