摘要
Objective To evaluate the efficacy of a treatme nt modality for cervical interverte bral disc herniation which consiste d of aspiration of nucleus pulposus tissue in conjunction with nucleolysis by intravertebral disc injection of collagenase.Method From June 1997to June 2000,we excuted aspiration of interverte bral disc content followed by collagenase injection that resulted in chemical neclolysis of the remainder of the nucleus pulplsus tissue in 52patien ts with 94herniated intervertebral discs.Around 600u (1ml )of collagenase per intervertebral d isc was used.The success with this treatmen t was judged by clinical observation and imaging means.Results Follow-up study ranging from 6month s to24months revealed excellent and goo d results in 90%of all patients with a ny complications.Preoperative and postoperative lateral X-ray films o f the cervical spine in hyperextensio n and hyperflexion were taken which s howed no remarkable alterations in t he stability status.Conclusions Aspiration plus nucleolysis by means of intraintervertebral disc colla genase is safe and effective for some patients with cervical interverteb ral disc herniation.
Objective To evaluate the efficacy of a treatme nt modality for cervical interverte bral disc herniation which consiste d of aspiration of nucleus pulposus tissue in conjunction with nucleolysis by intravertebral disc injection of collagenase.Method From June 1997to June 2000,we excuted aspiration of interverte bral disc content followed by collagenase injection that resulted in chemical neclolysis of the remainder of the nucleus pulplsus tissue in 52patien ts with 94herniated intervertebral discs.Around 600u (1ml )of collagenase per intervertebral d isc was used.The success with this treatmen t was judged by clinical observation and imaging means.Results Follow-up study ranging from 6month s to24months revealed excellent and goo d results in 90%of all patients with a ny complications.Preoperative and postoperative lateral X-ray films o f the cervical spine in hyperextensio n and hyperflexion were taken which s howed no remarkable alterations in t he stability status.Conclusions Aspiration plus nucleolysis by means of intraintervertebral disc colla genase is safe and effective for some patients with cervical interverteb ral disc herniation.
出处
《中国临床康复》
CSCD
2002年第4期614-614,共1页
Chinese Journal of Clinical Rehabilitation