体外循环预充血定安对预充液胶体渗透压的影响

The effect of gelofusine for colloid osmosis pressure during cardiopulmonary bypass

目的 :观察体外循环中预充血定安对预充液胶体渗透压的影响。方法 :10例 (实验组 )心内直视术患者体外循环预充液总量的 3 4采用血定安 ,另 1 4采用平衡盐、4 %碳酸氢钠和 2 0 %甘露醇 ;同时和 10例 (对照组 )体外循环预充液总量的 3 4采用平衡盐 ,另 1 4采用血浆、4 %碳酸氢钠和 2 0 %甘露醇的患者比较 ;观察体外循环中血定安对预充液的胶体渗透压的影响。结果 :在基本相同的条件下 ,实验组的胶体渗透压比对照组的胶体渗透压显著增高 ,2组相比有明显的差异性 (P <0 0 0 1)。结论

Objective:To observe the effect of Gelofusine for colloid osmosis pressure(COP) during cardiopulmonary bypass.Method:In test group (10 cases),the 3/4 volume of total prince was Gelofusine.The other 1/4 volume contain 4% NaHCO\-3,20% Mannitol.In control group (10 cases),The 3/4 volume of total volume was crystal,the other 1/4 volume contain 4% NaHCO\-3 (50～100 ml),20% Mannitol (50～100 ml),blood plasma (200～250 ml).To observe the effect of Gelofusine for COP during CPB.Result:In the same condition,the average COP in test group was much higher than control group ( P <0 001).Conclusion:Large\|dose Gelofusine could rise COP during CPB.