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恶性肿瘤的瘤苗免疫治疗 被引量:2

Cancer Immunotherapy with Tumor-cell Vaccine
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摘要 恶性肿瘤的瘤苗免疫治疗 ,是指应用肿瘤细胞或经各种基因修饰后的肿瘤细胞在体外制成瘤苗 ,经致死性剂量照射后 ,重新接种于患者体内 ,使逃避免疫监视的肿瘤细胞可以被免疫系统识别 ,从而诱导机体产生针对肿瘤细胞的主动的、特异性的免疫反应。目前 ,瘤苗免疫治疗已有很多成功的动物模型 ,人体的临床试验也取得了肯定的疗效。但如何进一步提高免疫效果 。
作者 秦燕 宋三泰
出处 《国外医学(肿瘤学分册)》 2002年第1期36-39,共4页 Foreign Medical Sciences (Cancer Section)
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参考文献15

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同被引文献14

  • 1王艳,周乐,耿宜平,司履生,王一理.低免疫原性肿瘤可诱导调节性T细胞增生[J].中华病理学杂志,2005,34(9):583-587. 被引量:3
  • 2HarrisJE, et al. Adjuvant active specific immunotherapy for stage Ⅱ and Ⅲ colon cancer with an autologous tumor cell caccine:Eastem Coperative Oncology Group Study E5283[J]. J Clin Oncol, 2000,18(1):148~157.
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  • 10Harris JE,Ryan L,Hoover HC Jr,et al.Adjuvant active specific immunotherapy for stage Ⅱ and Ⅲ colon cancer with an autologous tumor cell vaccine:Eastern Cooperative Oncology Group Study E5283[J].J Clin Oncol,2000,18(1):148-157.

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