摘要
目的总结直线加速器立体定向放射外科治疗脑转移瘤的临床效果。方法采用德国BrainScanX刀系统治疗脑转移瘤165例,肿瘤平均周边剂量15~25Gy,通常以60%~90%的剂量曲线覆盖肿瘤的边缘。其中有45例配合全脑放疗。结果随访3~24个月约124例行CT、MR检查证实肿瘤消失(CR)54例(43.5%)、大部分消失(PR)28例(22.6%),部分消失(MR)20例(16.1%),无变化(NC)16例(12.9%),增大(PG)6例(4.8%)。临床随访130例,有94例死亡,平均存活期11.3±6.0个月,生存36例,已平均存活9.5月。结论直线加速器立体放射外科治疗脑转移瘤近期疗效满意,是一种安全有效的方法。
Objective To summarize clinical effect of the stererotaxic surgery therapy for encephalon metastases by beeline accelerator.Methods 165 patients of encephalon metastases were treated by Germany BrainScan X reamer system with average circumferential dosage 15~25 Gy to metastases and generally with 60%~90%dose curve covering the tumor edge. Among them 45 cases were treated by adjuvant whole brain irradiation. Results After 3~24 months follow-up for the 124 cases examined by CT or MR, 54 cases (43.5%) metastases disappeared (CR), 28 cases (22.6%) metastases disappeared mostly (PR), 20 cases (16.1%) metastases disappeared partly, 16 cases (12.9%) metastases changed nothing and 6 cases(4.8%) metastases enlarged (PG). Among 130 cases of clinical follow-up, 94 cases were death with the average living-time 11.3±6.0 months and 36 survival have been alive for 9.5 months averagely. Conclusions To treat encephalon metastases by beeline accelerator stereotaxic radiosurgry is a safe and effective therapy method and has satisfactory curative effect in the near future.
出处
《中国航天医药杂志》
2002年第1期29-30,共2页
Medical Journal of CASE