压缩雾化吸入沙丁胺醇和异丙托溴铵治疗毛细支气管炎

Clinical observation on the treatment of 50 cases with bronchiolitis using compressed-nebulized-inhalation of salbutamol and ipratropine

目的:探讨压缩雾化吸入沙丁胺醇和异丙托溴铵对毛细支气管炎(毛支)的疗效。方法:毛支患儿100例随机分为两组,对照组50例采用常规治疗,治疗组50例在常规治疗的基础上加用雾化治疗,观察两组解除主要症状(喘憋)和体征(肺部喘鸣音)的时间和住院时间。结果:治疗组住院时间和喘憋、肺部喘鸣音的持续时间均明显短于对照组(P<0.01)。结论:压缩雾化吸入沙丁胺醇和异丙托溴铵治疗毛支疗效确切,方法简便,副作用小,值得推广。

Objective: To explore the therapeutic efficacy of compressed-nebulized-inhalation of salbutamol and ipratropine on bronchiolitis. Methods: 100 cases of bronchiolitis were divided randomly into 2 groups: control group(n=50) treated with tradition therapy and treatment group (n=50) treated with salbutamol and ipratropine besides tradition therapy, then determined disapper time of symptoms and signs and average period of treatment. Results: The average period of treatment and of disappearing of symptoms in treatment group were obviously shorter than in control one(P< 0.01). Conclusion: Compressed-nebulized-inhalation of salbutamol and ipratropine is really efficacious for treatment of bronchiolitis, with less side-effect and easy operation,and is worth clinical application.