更昔洛韦治疗婴儿巨细胞病毒性肝炎

Adjuvant treatment of cytomegaloviral hepatitis with ganciclovir

目的:探讨更昔洛韦治疗婴儿巨细胞病毒性肝炎的治疗效果。方法:对50例确诊巨细胞病毒性肝炎的患儿随机分成对照组与治疗组,均给予保肝等对症处理,另外治疗组加用更昔洛韦7.5mg/kg,2次/日,连用14d。结果:对照组与治疗组肝功能、黄疸消退有显著差异(P<0.05)。治疗组治愈率80%与对照组有显著差异(P<0.01)。结论:更昔洛韦是治疗婴儿巨细胞病毒性肝炎的有效药物。

Objective: To estimate the adjuvant treatment of cytomegaloviral hepatitis with ganciclovir. Methods: Fifty patients were randomly divided into two groups. Twenty-five patients of treatment group were given 7.5 mg / kg ganciclovir, q 12 h, for fourteen day besides synthetic treatment. Twenty-five of control groups were given synthetic treatment. Results: The changes of ALT and TBIL in treatment group were superior to that in control group (P< 0.05). The cure rate of treatment group were 80% (P< 0.01). Conclusion: The ganciclovir has a good efficacy for treatment of cytomegaloviral hepatitis.