干扰素治疗秋季腹泻40例疗效观察

Observing The therapeutic effect of interferon in 40 cases of autumn diarrhea

目的:探讨秋季腹泻有效的治疗措施。方法:秋季腹泻患儿80例,随机分为治疗组与对照组各40例。治疗组加用α-干扰素5万u/kg肌注,每日一次,连用3d。对照组仅用双黄连、利巴韦林静滴等常规治疗。结果:72h止泻率治疗组为95%,对照组为72.5%(P<0.01)。治疗组与对照组止泻时间分别为39.5±13.6h和52.5±14.9h(P<0.01),两组比较有显著性差异。结论:干扰素治疗秋季腹泻在病程和病情改善方面优于其他抗病毒药,值得临床推广。

Objectives: To search for the effective therapy of autumn diarrhea. Methods: 80 children patients with autumn diarrhea were randomly divided into two groups, therapy group with 40 cases and control group with 40 cases, with interferon α 50 thousand IU/kg intramuscular injection in therapy group once a day, total 3day and with Shuang Huang Lian & ribavirini added into 100～150 ml 10% G.S solution, interavenous drip in control group,once a day. Results: The rate of stopping diarrhea in seventy-two hours is 95% in therapy group and 72.5% in control (P< 0.01) . The time of stopping diarrhea is respctively 39.5±13.6 and 52.5±14.9 hours in the two groups. There is a significant difference between the two groups (P< 0.01). Conclusion: Interferon α in treating autumn diarrhea is better than the other antivirus in the course and develapment of the case , and is worthy of applyeation.